Cancer Metabolism

Oxythiamine and dehydroepiandrosterone inhibit the nonoxidative synthesis of ribose and tumor cell proliferation. Cancer Res. 1997 Oct 1;57(19):4242-8. PMID: 9331084

Gleevec (STI571) influences metabolic enzyme activities and glucose carbon flow toward nucleic acid and fatty acid synthesis in myeloid tumor cells. J Biol Chem. 2001 Oct 12;276(41):37747-53. PMID: 11489902

A metabolic hypothesis of cell growth and death in pancreatic cancer. Pancreas. 2002 Jan;24(1):26-33. Review. PMID: 11741179

K-ras codon-specific mutations produce distinctive metabolic phenotypes in NIH3T3 mice [corrected] fibroblasts. Cancer Res. 2005 Jul 1;65(13):5512-5. Erratum in: Cancer Res. 2005 Sep 1;65(17):8057. PMID: 15994921

[1,2-13C2]-D-glucose profiles of the serum, liver, pancreas, and DMBA-induced pancreatic tumors of rats. Pancreas. 2005 Nov;31(4):337-43. PMID: 16258367

Pentose phosphate cycle oxidative and nonoxidative balance: A new vulnerable target for overcoming drug resistance in cancer. Int J Cancer.119(12):2733-41, 2006. PMID: 17019714

Direct spectrophotometric determination of serum fructose in pancreatic cancer patients.
Pancreas. 2009 Aug;38(6):706-12. doi: 10.1097/MPA.0b013e3181a7c6e5.
PMID: 19506535

Abnormalities in glucose uptake and metabolism in imatinib-resistant human BCR-ABL-positive cells. Clin Cancer Res. 2009 May 15;15(10):3442-50. doi: 10.1158/1078-0432.CCR-08-3291. PMID: 19401345

Fructose induces transketolase flux to promote pancreatic cancer growth.
Cancer Res. 2010 Aug 1;70(15):6368-76. doi: 10.1158/0008-5472.CAN-09-4615. Epub 2010 Jul 20.

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